2013
Arnlov J, Carlsson AC, Sundstrom J, Ingelsson E, Larsson A, Lind L and Larsson TE (2013). Serum FGF23 and risk of cardiovascular events in relation to mineral metabolism and cardiovascular pathology. Clin J Am Soc Nephrol. 8: 781-6. PubMed
Arnlov J, Carlsson AC, Sundstrom J, Ingelsson E, Larsson A, Lind L and Larsson TE (2013). Higher fibroblast growth factor-23 increases the risk of all-cause and cardiovascular mortality in the community. Kidney Int. 83: 160-6. PubMed
Arnlov J, Ruge T, Ingelsson E, Larsson A, Sundstrom J and Lind L (2013). Serum endostatin and risk of mortality in the elderly: findings from 2 community-based cohorts. Arterioscler Thromb Vasc Biol. 33: 2689-95. PubMed
Berndt SI, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, et al. (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 45: 501-12. PubMed
Carlsson AC, Larsson A, Helmersson-Karlqvist J, Lind L, Ingelsson E, Larsson TE, Sundstrom J and Arnlov J (2013). Urinary kidney injury molecule 1 and incidence of heart failure in elderly men. Eur J Heart Fail. 15: 441-6. PubMed
Carlsson AC, Ruge T, Sundstrom J, Ingelsson E, Larsson A, Lind L and Arnlov J (2013). Association between circulating endostatin, hypertension duration, and hypertensive target-organ damage. Hypertension. 62: 1146-51. PubMed
Consortium CAD, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, Konig IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, et al. (2013). Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 45: 25-33. PubMed
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segre AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, et al. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 45: 621-31. PubMed
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T, et al. (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 45: 1345-52. PubMed
Eggers KM, Al-Shakarchi J, Berglund L, Lindahl B, Siegbahn A, Wallentin L and Zethelius B (2013). High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men. Am Heart J. 166: 541-8. PubMed
Fall T, Hagg S, Magi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, Mangino M, Sonestedt E, Benyamin B, Nelson CP, Rivera NV, et al. (2013). The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med. 10: e1001474. PubMed
Ganna A, Magnusson PK, Pedersen NL, de Faire U, Reilly M, Arnlov J, Sundstrom J, Hamsten A and Ingelsson E (2013). Multilocus genetic risk scores for coronary heart disease prediction. Arterioscler Thromb Vasc Biol. 33: 2267-72. PubMed
Gao H, Fall T, van Dam RM, Flyvbjerg A, Zethelius B, Ingelsson E and Hagg S (2013). Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study. Diabetes. 62: 1338-44. PubMed
Global Lipids Genetics C, Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, et al. (2013). Discovery and refinement of loci associated with lipid levels. Nat Genet. 45: 1274-83. PubMed
Helmersson-Karlqvist J, Arnlov J and Larsson A (2013). Day-to-day variation of urinary NGAL and rational for creatinine correction. Clin Biochem. 46: 70-2. PubMed
Helmersson-Karlqvist J, Larsson A, Carlsson AC, Venge P, Sundstrom J, Ingelsson E, Lind L and Arnlov J (2013). Urinary neutrophil gelatinase-associated lipocalin (NGAL) is associated with mortality in a community-based cohort of older Swedish men. Atherosclerosis. 227: 408-13. PubMed
Hruby A, Ngwa JS, Renstrom F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimaki T, Lemaitre RN, Manichaikul A, North KE, Ntalla I, Sonestedt E, Tanaka T, van Rooij FJ, Bandinelli S, Djousse L, Grigoriou E, et al. (2013). Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. J Nutr. 143: 345-53. PubMed
Huang X, Jimenez-Moleon JJ, Lindholm B, Cederholm T, Arnlov J, Riserus U, Sjogren P and Carrero JJ (2013). Mediterranean diet, kidney function, and mortality in men with CKD. Clin J Am Soc Nephrol. 8: 1548-55. PubMed
Jobs E, Riserus U, Ingelsson E, Sundstrom J, Jobs M, Nerpin E, Iggman D, Basu S, Larsson A, Lind L and Arnlov J (2013). Serum cathepsin S is associated with decreased insulin sensitivity and the development of type 2 diabetes in a community-based cohort of elderly men. Diabetes Care. 36: 163-5. PubMed
Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A, Djousse L, Ngwa JS, Follis JL, Dimitriou M, Ganna A, Houston DK, Kanoni S, Mikkila V, Manichaikul A, Ntalla I, Renstrom F, Sonestedt E, et al. (2013). Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol. 177: 103-15. PubMed
Nitsch D, Grams M, Sang Y, Black C, Cirillo M, Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Oien CM, Levey AS, Levin A, Woodward M, Hemmelgarn BR and Chronic Kidney Disease Prognosis C (2013). Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis. BMJ. 346: f324. PubMed
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpelainen TO, Esko T, Magi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, et al. (2013). Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 9: e1003500. PubMed
Shlipak MG, Matsushita K, Arnlov J, Inker LA, Katz R, Polkinghorne KR, Rothenbacher D, Sarnak MJ, Astor BC, Coresh J, Levey AS, Gansevoort RT and Consortium CKDP (2013). Cystatin C versus creatinine in determining risk based on kidney function. N Engl J Med. 369: 932-43. PubMed
Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, Wormser D, Kaptoge S, Whitlock G, Qiao Q, Lewington S, Di Angelantonio E, Vander Hoorn S, Lawes CM, Ali MK, Mozaffarian D, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating G, Asia-Pacific Cohort Studies C, Diabetes Epidemiology: Collaborative analysis of Diagnostic criteria in E, Emerging Risk Factor C, et al. (2013). The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One. 8: e65174. PubMed
Song C, Pedersen NL, Reynolds CA, Sabater-Lleal M, Kanoni S, Willenborg C, Consortium CAD, Syvanen AC, Watkins H, Hamsten A, Prince JA and Ingelsson E (2013). Genetic variants from lipid-related pathways and risk for incident myocardial infarction. PLoS One. 8: e60454. PubMed
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaelsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, et al. (2013). Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 10: e1001383. PubMed
Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancakova A, Buxbaum SG, Lyytikainen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, et al. (2013). Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PubMed
2012
Arefalk G, Hergens MP, Ingelsson E, Arnlov J, Michaelsson K, Lind L, Ye W, Nyren O, Lambe M and Sundstrom J (2012). Smokeless tobacco (snus) and risk of heart failure: results from two Swedish cohorts. Eur J Prev Cardiol. 19: 1120-7. PubMed
Berglund L, Berne C, Svardsudd K, Garmo H, Melhus H and Zethelius B (2012). Seasonal variations of insulin sensitivity from a euglycemic insulin clamp in elderly men. Ups J Med Sci. 117: 35-40. PubMed
Byberg L, Gedeborg R, Cars T, Sundstrom J, Berglund L, Kilander L, Melhus H and Michaelsson K (2012). Prediction of fracture risk in men: a cohort study. J Bone Miner Res. 27: 797-807. PubMed
Collaboration IRGCERF, Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN, Gao P, Saleheen D, Rendon A, Nelson CP, Braund PS, Hall AS, Chasman DI, Tybjaerg-Hansen A, Chambers JC, Benjamin EJ, Franks PW, Clarke R, Wilde AA, et al. (2012). Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 379: 1205-13. PubMed
Emerging Risk Factors C, Di Angelantonio E, Gao P, Pennells L, Kaptoge S, Caslake M, Thompson A, Butterworth AS, Sarwar N, Wormser D, Saleheen D, Ballantyne CM, Psaty BM, Sundstrom J, Ridker PM, Nagel D, Gillum RF, Ford I, Ducimetiere P, Kiechl S, et al. (2012). Lipid-related markers and cardiovascular disease prediction. JAMA. 307: 2499-506. PubMed
Emerging Risk Factors C, Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Bjorkelund C, Brenner H, et al. (2012). C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med. 367: 1310-20. PubMed
Fall T, Arnlov J, Berne C and Ingelsson E (2012). The role of obesity-related genetic loci in insulin sensitivity. Diabet Med. 29: e62-6. PubMed
Forsberg LA, Rasi C, Razzaghian HR, Pakalapati G, Waite L, Thilbeault KS, Ronowicz A, Wineinger NE, Tiwari HK, Boomsma D, Westerman MP, Harris JR, Lyle R, Essand M, Eriksson F, Assimes TL, Iribarren C, Strachan E, O'Hanlon TP, Rider LG, et al. (2012). Age-related somatic structural changes in the nuclear genome of human blood cells. Am J Hum Genet. 90: 217-28. PubMed
Fox CS, Matsushita K, Woodward M, Bilo HJ, Chalmers J, Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP, Nelson RG and Chronic Kidney Disease Prognosis C (2012). Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet. 380: 1662-73. PubMed
Hallan SI, Matsushita K, Sang Y, Mahmoodi BK, Black C, Ishani A, Kleefstra N, Naimark D, Roderick P, Tonelli M, Wetzels JF, Astor BC, Gansevoort RT, Levin A, Wen CP, Coresh J and Chronic Kidney Disease Prognosis C (2012). Age and association of kidney measures with mortality and end-stage renal disease. JAMA. 308: 2349-60. PubMed
Jacobsson JA, Rask-Andersen M, Riserus U, Moschonis G, Koumpitski A, Chrousos GP, Lannfelt L, Marcus C, Gyllensten U, Schioth HB and Fredriksson R (2012). Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children. Int J Obes (Lond). 36: 119-29. PubMed
Khanolkar A, Vagero D and Koupil I (2012). Social determinants of cardiac disease biomarkers: investigating a Swedish male cohort at ages 50 and 70. Eur J Prev Cardiol. 19: 523-33. PubMed
Mahmoodi BK, Matsushita K, Woodward M, Blankestijn PJ, Cirillo M, Ohkubo T, Rossing P, Sarnak MJ, Stengel B, Yamagishi K, Yamashita K, Zhang L, Coresh J, de Jong PE, Astor BC and Chronic Kidney Disease Prognosis C (2012). Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis. Lancet. 380: 1649-61. PubMed
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, et al. (2012). A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 44: 659-69. PubMed
Matsushita K, Mahmoodi BK, Woodward M, Emberson JR, Jafar TH, Jee SH, Polkinghorne KR, Shankar A, Smith DH, Tonelli M, Warnock DG, Wen CP, Coresh J, Gansevoort RT, Hemmelgarn BR, Levey AS and Chronic Kidney Disease Prognosis C (2012). Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 307: 1941-51. PubMed
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J, et al. (2012). Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 44: 981-90. PubMed
Nerpin E, Helmersson-Karlqvist J, Riserus U, Sundstrom J, Larsson A, Jobs E, Basu S, Ingelsson E and Arnlov J (2012). Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study. BMC Res Notes. 5: 537. PubMed
Rapsomaniki E, White IR, Wood AM, Thompson SG and Emerging Risk Factors C (2012). A framework for quantifying net benefits of alternative prognostic models. Stat Med. 31: 114-30. PubMed
Ronnemaa E, Zethelius B, Vessby B, Lannfelt L, Byberg L and Kilander L (2012). Serum fatty-acid composition and the risk of Alzheimer's disease: a longitudinal population-based study. Eur J Clin Nutr. 66: 885-90. PubMed
Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tonjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, Rasmussen-Torvik LJ, Stringham HM, Tanaka T, Aadahl M, Arking DE, et al. (2012). No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes. 61: 1291-6. PubMed
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Magi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PC, Jukema JW, Johnson T, et al. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet. 44: 991-1005. PubMed
Wiberg B, Kilander L, Sundstrom J, Byberg L and Lind L (2012). The relationship between executive dysfunction and post-stroke mortality: a population-based cohort study. BMJ Open. 2: PubMed
2011
Basu S, Zethelius B, Helmersson J, Berne C, Larsson A and Ärnlöv J (2011).Cytokine-mediated inflammation is independently associated with insulin sensitivity measured by the euglycemic insulin clamp in a community-based cohort of elderly men. Int J Clin Exp Med. 4: 164-8. PubMed
Benedict C, Jacobsson JA, Rönnemaa E, Sällman-Almén M, Brooks S, Schultes B, Fredriksson R, Lannfelt L, Kilander L and Schiöth HB (2011). The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men. Neurobiol Aging. 32: 1159.e1-5. PubMed
Burgaz A, Byberg L, Rautiainen S, Orsini N, Håkansson N, Ärnlöv J, Sundström J, Lind L, Melhus H, Michaëlsson K and Wolk A (2011). Confirmed hypertension and plasma 25(OH)D concentrations amongst elderly men. J Intern Med. 269: 211-8. PubMed
Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, et al. (2011). CUBN is a gene locus for albuminuria. J Am Soc Nephrol. 22: 555-70. PubMed
Grundmark B, Zethelius B, Garmo H and Holmberg L (2011). Serum levels of selenium and smoking habits at age 50 influence long term prostate cancer risk; a 34 year ULSAM follow-up. BMC Cancer. 11: 431. PubMed
Hansson J, Vasan RS, Ärnlöv J, Ingelsson E, Lind L, Larsson A, Michaëlsson K and Sundström J (2011). Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study. PLoS One. 6: e16185. PubMed
Jobs E, Ingelsson E, Risérus U, Nerpin E, Jobs M, Sundström J, Basu S, Larsson A, Lind L and Ärnlöv J (2011). Association between serum cathepsin S and mortality in older adults. JAMA. 306: 1113-21. PubMed
Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, et al. (2011). Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes. 60: 2407-16. PubMed
Kilpeläinen TO, Zillikens MC, Stancákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, et al. (2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 43: 753-60.PubMed
Nathanson D, Zethelius B, Berne C, Lind L, Andrén B, Ingelsson E, Holst JJ and Nyström T (2011). Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men. Diabet Med. 28: 301-5. PubMed
Nerpin E, Ingelsson E, Risérus U, Sundström J, Larsson A, Jobs E, Jobs M, Hallan S, Zethelius B, Berglund L, Basu S and Ärnlöv J (2011). The combined contribution of albuminuria and glomerular filtration rate to the prediction of cardiovascular mortality in elderly men. Nephrol Dial Transplant. 26: 2820-7. PubMed
Rönnemaa E, Zethelius B, Lannfelt L and Kilander L (2011). Vascular risk factors and dementia: 40-year follow-up of a population-based cohort. Dement Geriatr Cogn Disord. 31: 460-6. PubMed
Seshasai SR, Kaptoge S, Thompson A, Di Angelantonio E, Gao P, Sarwar N, Whincup PH, Mukamal KJ, Gillum RF, Holme I, Njølstad I, Fletcher A, Nilsson P, Lewington S, Collins R, et al. (2011). Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med. 364: 829-41. PubMed
Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, et al. (2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 60: 2624-34.PubMed
Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, Sarwar N, Kizer JR, Lawlor DA, Nordestgaard BG, Ridker P, Salomaa V, Stevens J, Woodward M, Sattar N, et al. (2011). Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet. 377: 1085-95.PubMed
Ärnlöv J, Sundström J, Ingelsson E and Lind L (2011). Impact of BMI and the metabolic syndrome on the risk of diabetes in middle-aged men. Diabetes Care. 34: 61-5. PubMed
2010
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, et al. (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 42: 105-16. PubMed
Grundmark B, Garmo H, Loda M, Busch C, Holmberg L and Zethelius B (2010).The metabolic syndrome and the risk of prostate cancer under competing risks of death from other causes. Cancer Epidemiol Biomarkers Prev. 19: 2088-96. PubMed
Gustafsson S, Lind L, Zethelius B, Venge P, Flyvbjerg A, Söderberg S and Ingelsson E (2010). Adiponectin and cardiac geometry and function in elderly: results from two community-based cohort studies. Eur J Endocrinol. 162: 543-50. PubMed
Hagström E, Ingelsson E, Sundström J, Hellman P, Larsson TE, Berglund L, Melhus H, Held C, Michaëlsson K, Lind L and Ärnlöv J (2010). Plasma parathyroid hormone and risk of congestive heart failure in the community. Eur J Heart Fail. 12: 1186-92. PubMed
Iggman D, Ärnlöv J, Vessby B, Cederholm T, Sjögren P and Risérus U (2010).Adipose tissue fatty acids and insulin sensitivity in elderly men.Diabetologia. 53: 850-7. PubMed
Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, et al. (2010). Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 59: 1266-75. PubMed
Jobs E, Risérus U, Ingelsson E, Helmersson J, Nerpin E, Jobs M, Sundström J, Lind L, Larsson A, Basu S and Ärnlöv J (2010). Serum cathepsin S is associated with serum C-reactive protein and interleukin-6 independently of obesity in elderly men. J Clin Endocrinol Metab. 95: 4460-4. PubMed
Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, Danesh J and Collaboration ERF (2010). C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet. 375: 132-40. PubMed
Larsson TE, Olauson H, Hagström E, Ingelsson E, Ärnlöv J, Lind L and Sundström J (2010). Conjoint effects of serum calcium and phosphate on risk of total, cardiovascular, and noncardiovascular mortality in the community.Arterioscler Thromb Vasc Biol. 30: 333-9. PubMed
Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, Gansevoort RT and Consortium CKDP (2010). Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet. 375: 2073-81. PubMed
Melhus H, Snellman G, Gedeborg R, Byberg L, Berglund L, Mallmin H, Hellman P, Blomhoff R, Hagström E, Ärnlöv J and Michaëlsson K (2010). Plasma 25-hydroxyvitamin D levels and fracture risk in a community-based cohort of elderly men in Sweden. J Clin Endocrinol Metab. 95: 2637-45. PubMed
Michaëlsson K, Baron JA, Snellman G, Gedeborg R, Byberg L, Sundström J, Berglund L, Ärnlöv J, Hellman P, Blomhoff R, Wolk A, Garmo H, Holmberg L and Melhus H (2010). Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr. 92: 841-8.PubMed
Nathanson D, Zethelius B, Berne C, Holst JJ, Sjöholm A and Nyström T (2010).Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease. Diabetologia. 53: 277-80. PubMed
Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, van Rooij FJ, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, Garcia M, Anderson JS, Follis JL, Djousse L, et al. (2010). Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care. 33: 2684-91.PubMed
Petersson H, Ärnlöv J, Zethelius B and Risérus U (2010). Serum fatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men. Diabetes Res Clin Pract. 87: 379-84. PubMed
Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J and Collaboration ERF (2010).Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 375: 2215-22. PubMed
Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J, Consortium TCDG and Collaboration ERF (2010). Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet. 375: 1634-9. PubMed
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, et al. (2010). Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet. 42: 142-8. PubMed
Sjögren P, Becker W, Warensjö E, Olsson E, Byberg L, Gustafsson IB, Karlström B and Cederholm T (2010). Mediterranean and carbohydrate-restricted diets and mortality among elderly men: a cohort study in Sweden. Am J Clin Nutr. 92: 967-74. PubMed
Thompson S, Kaptoge S, White I, Wood A, Perry P, Danesh J and Collaboration ERF (2010). Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies. Int J Epidemiol. 39: 1345-59. PubMed
Wiberg B, Lind L, Kilander L, Zethelius B, Sundelöf JE and Sundström J (2010).Cognitive function and risk of stroke in elderly men. Neurology. 74: 379-85.PubMed
Ärnlöv J, Ingelsson E, Sundström J and Lind L (2010). Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men. Circulation. 121: 230-6. PubMed
2009
Andersen LG, Angquist L, Gamborg M, Byberg L, Bengtsson C, Canoy D, Eriksson JG, Eriksson M, Järvelin MR, Lissner L, Nilsen TI, Osler M, Overvad K, Rasmussen F, Salonen MK, et al. (2009). Birth weight in relation to leisure time physical activity in adolescence and adulthood: meta-analysis of results from 13 nordic cohorts. PLoS One. 4: e8192. PubMed
Berglund L, Berne C, Svärdsudd K, Garmo H and Zethelius B (2009). Early insulin response and insulin sensitivity are equally important as predictors of glucose tolerance after correction for measurement errors. Diabetes Res Clin Pract. 86: 219-24. PubMed
Byberg L, Melhus H, Gedeborg R, Sundström J, Ahlbom A, Zethelius B, Berglund LG, Wolk A and Michaëlsson K (2009). Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort. Br J Sports Med. 43: 482. PubMed
Byberg L, Melhus H, Gedeborg R, Sundström J, Ahlbom A, Zethelius B, Berglund LG, Wolk A and Michaëlsson K (2009). Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort. BMJ. 338: b688. PubMed
Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK, Thompson A, Wood AM, Lewington S, Sattar N, Packard CJ, Collins R, Thompson SG, Danesh J and Collaboration ERF (2009). Major lipids, apolipoproteins, and risk of vascular disease. JAMA. 302: 1993-2000. PubMed
Erqou S, Kaptoge S, Perry PL, Di Angelantonio E, Thompson A, White IR, Marcovina SM, Collins R, Thompson SG, Danesh J and Collaboration ERF (2009).Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 302: 412-23. PubMed
Giedraitis V, Kilander L, Degerman-Gunnarsson M, Sundelöf J, Axelsson T, Syvänen AC, Lannfelt L and Glaser A (2009). Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. Dement Geriatr Cogn Disord. 27: 59-68. PubMed
Hagström E, Hellman P, Larsson TE, Ingelsson E, Berglund L, Sundström J, Melhus H, Held C, Lind L, Michaëlsson K and Ärnlöv J (2009). Plasma parathyroid hormone and the risk of cardiovascular mortality in the community.Circulation. 119: 2765-71. PubMed
Helmersson J, Ärnlöv J, Axelsson T and Basu S (2009). A polymorphism in the cyclooxygenase 1 gene is associated with decreased inflammatory prostaglandin F2alpha formation and lower risk of cardiovascular disease.Prostaglandins Leukot Essent Fatty Acids. 80: 51-6. PubMed
Helmersson J, Ärnlöv J, Larsson A and Basu S (2009). Low dietary intake of beta-carotene, alpha-tocopherol and ascorbic acid is associated with increased inflammatory and oxidative stress status in a Swedish cohort. Br J Nutr. 101: 1775-82. PubMed
Hyvärinen M, Qiao Q, Tuomilehto J, Laatikainen T, Heine RJ, Stehouwer CD, Alberti KG, Pyörälä K, Zethelius B, Stegmayr B and Group DS (2009).Hyperglycemia and stroke mortality: comparison between fasting and 2-h glucose criteria. Diabetes Care. 32: 348-54. PubMed
Hyvärinen M, Tuomilehto J, Mähönen M, Stehouwer CD, Pyörälä K, Zethelius B, Qiao Q and Group DS (2009). Hyperglycemia and incidence of ischemic and hemorrhagic stroke-comparison between fasting and 2-hour glucose criteria. Stroke. 40: 1633-7. PubMed
Ingelsson E, Sundström J, Melhus H, Michaëlsson K, Berne C, Vasan RS, Risérus U, Blomhoff R, Lind L and Ärnlöv J (2009). Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly. Atherosclerosis. 206: 239-44. PubMed
Ingelsson E, Ärnlöv J, Sundström J, Risérus U, Michaëlsson K and Byberg L (2009). Relative importance and conjoint effects of obesity and physical inactivity for the development of insulin resistance. Eur J Cardiovasc Prev Rehabil. 16: 28-33. PubMed
Ingelsson E, Ärnlöv J, Zethelius B, Vasan RS, Flyvbjerg A, Frystyk J, Berne C, Hänni A, Lind L and Sundström J (2009). Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity. J Clin Endocrinol Metab. 94: 953-7. PubMed
Jacobsson JA, Risérus U, Axelsson T, Lannfelt L, Schiöth HB and Fredriksson R (2009). The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924. BMC Med Genet. 10: 131. PubMed
Nydahl M, Gustafsson IB, Mohsen R and Becker W (2009). Comparison between optical readable and open-ended weighed food records. Food Nutr Res. 53. PubMed
Ostman B, Michaëlsson K, Helmersson J, Byberg L, Gedeborg R, Melhus H and Basu S (2009). Oxidative stress and bone mineral density in elderly men: antioxidant activity of alpha-tocopherol. Free Radic Biol Med. 47: 668-73.PubMed
Qiao Q, Laatikainen T, Zethelius B, Stegmayr B, Eliasson M, Jousilahti P and Tuomilehto J (2009). Comparison of definitions of metabolic syndrome in relation to the risk of developing stroke and coronary heart disease in Finnish and Swedish cohorts. Stroke. 40: 337-43. PubMed
Rönnemaa E, Zethelius B, Sundelöf J, Sundström J, Degerman-Gunnarsson M, Lannfelt L, Berne C and Kilander L (2009). Glucose metabolism and the risk of Alzheimer's disease and dementia: a population-based 12 year follow-up study in 71-year-old men. Diabetologia. 52: 1504-10. PubMed
Soveri I, Ärnlöv J, Berglund L, Lind L, Fellström B and Sundström J (2009).Kidney function and discrimination of cardiovascular risk in middle-aged men. J Intern Med. 266: 406-13. PubMed
Sundelöf J, Kilander L, Helmersson J, Larsson A, Rönnemaa E, Degerman-Gunnarsson M, Basun H, Lannfelt L and Basu S (2009). Systemic inflammation and the risk of Alzheimer's disease and dementia: a prospective population-based study. J Alzheimers Dis. 18: 79-87. PubMed
Sundelöf J, Kilander L, Helmersson J, Larsson A, Rönnemaa E, Degerman-Gunnarsson M, Sjögren P, Basun H, Lannfelt L and Basu S (2009). Systemic tocopherols and F2-isoprostanes and the risk of Alzheimer's disease and dementia: a prospective population-based study. J Alzheimers Dis. 18: 71-8.PubMed
Sundström J, Ingelsson E, Berglund L, Zethelius B, Lind L, Venge P and Ärnlöv J (2009). Cardiac troponin-I and risk of heart failure: a community-based cohort study. Eur Heart J. 30: 773-81. PubMed
Venge P, Ärnlöv J and Zethelius B (2009). Seemingly healthy 71-year-old men with minor elevations of cardiac troponin I and at risk of premature death in CVD have elevated levels of NT-proBNP: report from the ULSAM study.Scand J Clin Lab Invest. 69: 418-24. PubMed
Wiberg B, Sundström J, Zethelius B and Lind L (2009). Insulin sensitivity measured by the euglycaemic insulin clamp and proinsulin levels as predictors of stroke in elderly men. Diabetologia. 52: 90-6. PubMed
Ärnlöv J, Zethelius B, Risérus U, Basu S, Berne C, Vessby B, Alfthan G, Helmersson J and Men ULSoA (2009). Serum and dietary beta-carotene and alpha-tocopherol and incidence of type 2 diabetes mellitus in a community-based study of Swedish men: report from the Uppsala Longitudinal Study of Adult Men (ULSAM) study. Diabetologia. 52: 97-105.PubMed
2008
Auro K, Kristiansson K, Zethelius B, Berne C, Lannfelt L, Taskinen MR, Jauhiainen M, Perola M, Peltonen L and Syvänen AC (2008). USF1 gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study.Diabetologia. 51: 464-72. PubMed
Berglund L, Garmo H, Lindbäck J, Svärdsudd K and Zethelius B (2008). Maximum likelihood estimation of correction for dilution bias in simple linear regression using replicates from subjects with extreme first measurements. Stat Med. 27: 4397-407. PubMed
Dahlgren A, Lundmark P, Axelsson T, Lind L and Syvänen AC (2008). Association of the estrogen receptor 1 (ESR1) gene with body height in adult males from two Swedish population cohorts. PLoS One. 3: e1807. PubMed
Florvall G, Basu S, Helmersson J and Larsson A (2008). Microalbuminuria measured by three different methods, blood pressure and cardiovascular risk factors in elderly Swedish males. Anal Chem Insights. 3: 69-74. PubMed
Larsson A, Helmersson J, Hansson LO and Basu S (2008). Serum cystatin C is associated with other cardiovascular risk markers and cardiovascular disease in elderly men. Int J Cardiol. 125: 263-4. PubMed
Melhus H, Risérus U, Warensjö E, Wernroth L, Jensevik K, Berglund L, Vessby B and Michaëlsson K (2008). A high activity index of stearoyl-CoA desaturase is associated with increased risk of fracture in men. Osteoporos Int. 19: 929-34.PubMed
Michaëlsson K, Lind L, Frystyk J, Flyvbjerg A, Gedeborg R, Berne C, Zethelius B, Mallmin H, Söderberg S and Melhus H (2008). Serum adiponectin in elderly men does not correlate with fracture risk. J Clin Endocrinol Metab. 93: 4041-7.PubMed
Nerpin E, Risérus U, Ingelsson E, Sundström J, Jobs M, Larsson A, Basu S and Ärnlöv J (2008). Insulin sensitivity measured with euglycemic clamp is independently associated with glomerular filtration rate in a community-based cohort. Diabetes Care. 31: 1550-5. PubMed
Petersson H, Basu S, Cederholm T and Risérus U (2008). Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men. Br J Nutr. 99: 1186-9. PubMed
Rönnemaa E, Zethelius B, Sundelöf J, Sundström J, Degerman-Gunnarsson M, Berne C, Lannfelt L and Kilander L (2008). Impaired insulin secretion increases the risk of Alzheimer disease. Neurology. 71: 1065-71. PubMed
Sundelöf J, Giedraitis V, Irizarry MC, Sundström J, Ingelsson E, Rönnemaa E, Ärnlöv J, Gunnarsson MD, Hyman BT, Basun H, Ingelsson M, Lannfelt L and Kilander L (2008). Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study. Arch Neurol. 65: 256-63. PubMed
Sundelöf J, Ärnlöv J, Ingelsson E, Sundström J, Basu S, Zethelius B, Larsson A, Irizarry MC, Giedraitis V, Rönnemaa E, Degerman-Gunnarsson M, Hyman BT, Basun H, Kilander L and Lannfelt L (2008). Serum cystatin C and the risk of Alzheimer disease in elderly men. Neurology. 71: 1072-9. PubMed
Sundsten T, Zethelius B, Berne C and Bergsten P (2008). Plasma proteome changes in subjects with Type 2 diabetes mellitus with a low or high early insulin response. Clin Sci (Lond). 114: 499-507. PubMed
Warensjö E, Sundström J, Vessby B, Cederholm T and Risérus U (2008). Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: a population-based prospective study. Am J Clin Nutr. 88: 203-9. PubMed
Zethelius B, Berglund L, Hänni A and Berne C (2008). The interaction between impaired acute insulin response and insulin resistance predict type 2 diabetes and impairment of fasting glucose. Ups J Med Sci. 113: 117-29.PubMed
Zethelius B, Berglund L, Sundström J, Ingelsson E, Basu S, Larsson A, Venge P and Ärnlöv J (2008). Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N Engl J Med. 358: 2107-16. PubMed
2007
Berglund L, Garmo H, Lindbäck J and Zethelius B (2007). Correction for regression dilution bias using replicates from subjects with extreme first measurements. Stat Med. 26: 2246-57. PubMed
Dahlgren A, Zethelius B, Jensevik K, Syvänen AC, Berne C and Cohort U (2007).Variants of the TCF7L2 gene are associated with beta cell dysfunction and confer an increased risk of type 2 diabetes mellitus in the ULSAM cohort of Swedish elderly men. Diabetologia. 50: 1852-7. PubMed
Frystyk J, Berne C, Berglund L, Jensevik K, Flyvbjerg A and Zethelius B (2007).Serum adiponectin is a predictor of coronary heart disease: a population-based 10-year follow-up study in elderly men. J Clin Endocrinol Metab. 92: 571-6. PubMed
Gamborg M, Byberg L, Rasmussen F, Andersen PK, Baker JL, Bengtsson C, Canoy D, Drøyvold W, Eriksson JG, Forsén T, Gunnarsdottir I, Järvelin MR, Koupil I, Lapidus L, Nilsen TI, et al. (2007). Birth weight and systolic blood pressure in adolescence and adulthood: meta-regression analysis of sex- and age-specific results from 20 Nordic studies. Am J Epidemiol. 166: 634-45. PubMed
Hagström E, Hellman P, Lundgren E, Lind L and Ärnlöv J (2007). Serum calcium is independently associated with insulin sensitivity measured with euglycaemic-hyperinsulinaemic clamp in a community-based cohort.Diabetologia. 50: 317-24. PubMed
Ingelsson E, Lind L, Ärnlöv J and Sundström J (2007). Sleep disturbances independently predict heart failure in overweight middle-aged men. Eur J Heart Fail. 9: 184-90. PubMed
Ingelsson E, Sundström J, Lind L, Risérus U, Larsson A, Basu S and Ärnlöv J (2007). Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men. Eur Heart J. 28: 1739-45. PubMed
Koupil I (2007). The Uppsala studies on developmental origins of health and disease. J Intern Med. 261: 426-36. PubMed
Michaëlsson K, Olofsson H, Jensevik K, Larsson S, Mallmin H, Berglund L, Vessby B and Melhus H (2007). Leisure physical activity and the risk of fracture in men. PLoS Med. 4: e199. PubMed
Möller CS, Häggström J, Zethelius B, Wiberg B, Sundström J and Lind L (2007).Age and follow-up time affect the prognostic value of the ECG and conventional cardiovascular risk factors for stroke in adult men. J Epidemiol Community Health. 61: 704-12. PubMed
Pewsner D, Jüni P, Egger M, Battaglia M, Sundström J and Bachmann LM (2007).Accuracy of electrocardiography in diagnosis of left ventricular hypertrophy in arterial hypertension: systematic review. BMJ. 335: 711. PubMed
Risérus U and Ingelsson E (2007). Alcohol intake, insulin resistance, and abdominal obesity in elderly men. Obesity (Silver Spring). 15: 1766-73.PubMed
Risérus U, Ärnlöv J and Berglund L (2007). Long-term predictors of insulin resistance: role of lifestyle and metabolic factors in middle-aged men.Diabetes Care. 30: 2928-33. PubMed
Ström Möller C, Zethelius B, Sundström J and Lind L (2007). Persistent ischaemic ECG abnormalities on repeated ECG examination have important prognostic value for cardiovascular disease beyond established risk factors: a population-based study in middle-aged men with up to 32 years of follow-up. Heart. 93: 1104-10. PubMed
Warensjö E, Ingelsson E, Lundmark P, Lannfelt L, Syvänen AC, Vessby B and Risérus U (2007). Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity. Obesity (Silver Spring). 15: 1732-40.PubMed
Wohlin M, Helmersson J, Sundström J, Ärnlöv J, Vessby B, Larsson A, Andrén B, Lind L and Basu S (2007). Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness. Cytokine. 38: 130-6. PubMed
Wohlin M, Sundström J, Lannfelt L, Axelsson T, Syvänen AC, Andrén B, Basu S and Lind L (2007). Apolipoprotein E epsilon4 genotype is independently associated with increased intima-media thickness in a recessive pattern.Lipids. 42: 451-6. PubMed