Papers 2000-2006

2006

Florvall G, Basu S, Helmersson J, Larsson A. Hemocue urine albumin point-of-care test shows strong agreement with the results obtained with a large nephelometer. Diabetes Care. 2006;29 (2):422-3.

Ingelsson E, Ärnlöv J, Lind L, Sundström J. The metabolic syndrome and risk for heart failure in middle-aged men. Heart 2006; 92(10):1409-13.

Ingelsson E, Lind L, Ärnlöv J, Sundström J. Socioeconomic factors as predictors of incident heart failure. J Card Fail. 2006;12(7):540-5.

Ingelsson E, Lind L, Ärnlöv J, Sundström J. Sleep disturbances independently predict heart failure in overweight middle-aged men. Eur J Heart Fail 2006

Ingelsson E, Björklund-Bodegård K, Lind L, Ärnlöv J, Sundström J. Diurnal blood pressure pattern and risk of congestive heart failure. JAMA. 2006;295:2859-66

Ingelsson E, Risérus U, Berne C, Frystyk J, Flyvbjerg A, Axelsson T, Lundmark P, Zethelius B. Adiponectin and risk of congestive heart failure.
JAMA. 2006;295(15):1772-4.

Lind L, Vessby B, Sundström J. The apolipoprotein B/AI ratio and the metabolic syndrome independently predict risk for myocardial infarction in middle-aged men. Arterioscler Thromb Vasc Biol. 2006;26(2):406-10.

Möller CS, Zethelius B, Sundström J, Lind L. Impact of follow-up time and re-measurement of the electrocardiogram and conventional cardiovascular risk factors on their predictive value for myocardial infarction. J Intern Med. 2006l;260;:22-30.

Möller CS, Byberg L, Sundström J, Lind L. T wave abnormalities, high body mass index, current smoking and high lipoprotein (a) levels predict the development of major abnormal Q/QS patterns 20 years later. A population-based study. BMC Cardiovasc Disord. 2006; 6:10.

Sundström J, Vallhagen E, Risérus U, Byberg L, Zethelius B, Berne C, Lind L, Ingelsson E. Risk Associated With The Metabolic Syndrome Versus the Sum Of Its Individual Components. Diabetes Care 2006; 29(7):1673-4.

Sundström J, Risérus U, Byberg L, Zethelius B, Lithell H, Lind L. Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. BMJ. 2006 Apr 15;332 (7546):878-82.

Warensjö E, Sundström J, Lind L, Vessby B. Factor analysis of fatty acids in serum lipids as a measure of dietary fat quality in relation to the metabolic syndrome in men. Am J Clin Nutr. 2006 Aug;84(2):442-8.

Wiberg B, Sundstrom J, Arnlov J, Terent A, Vessby B, Zethelius B, Lind L. Metabolic risk factors for stroke and transient ischemic attacks in middle-aged men: a community-based study with long-term follow-up. Stroke. 2006 Dec;37(12):2898-903.

Zethelius B, Johnston N, Venge P. Troponin I as a predictor of coronary heart disease and mortality in 70-year-old men: a community-based cohort study. Circulation. 2006;113(8):1071-8.

 

2005

Ärnlöv J, Sundstrom J, Lind L, Andren B, Andersson M, Reneland R, Berglund L, Kashuba V, Protopopov A, Zabarovsky E, Lithell H. hUNC-93B1, a novel gene mainly expressed in the heart, is related to left ventricular diastolic function, heart failure morbidity and mortality in elderly men. Eur J Heart Fail. 2005;7:958-65.

Ärnlöv J, Lind L, Sundstrom J, Andren B, Vessby B, Lithell H. Insulin resistance, dietary fat intake and blood pressure predict left ventricular diastolic function 20 years later. Nutr Metab Cardiovasc Dis. 2005;15:242-9.

Ärnlöv J, Lind L, Andren B, Riserus U, Berglund L, Lithell H. A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men. Am Heart J. 2005;149:902-7.

Basu S, Helmersson J. Factors regulating isoprostane formation in vivo. Antioxid Redox Signal. 2005;7:221-35.

Florvall G, Basu S, Helmersson J, Larsson A. Hemocue urine albumin point-of-care test shows strong agreement with the results obtained with a large nephelometer. Diabetes Care. 2006;29:422-3.

Helmersson J, Ärnlöv J, Vessby B, Larsson A, Alfthan G, Basu S. Serum selenium predicts levels of F2-isoprostanes and prostaglandin F2alpha in a 27 year follow-up study of Swedish men. Free Radic Res. 2005;39:763-70.

Helmersson J, Vessby B, Larsson A, Basu S. Cyclooxygenase-mediated prostaglandin F2alpha is decreased in an elderly population treated with low-dose aspirin. Prostaglandins Leukot Essent Fatty Acids. 2005;72:227-33.

Helmersson J, Larsson A, Vessby B, Basu S. Active smoking and a history of smoking are associated with enhanced prostaglandin F(2alpha), interleukin-6 and F2-isoprostane formation in elderly men. Atherosclerosis. 2005;181:201-7.

Ingelsson E, Ärnlöv J, Sundstrom J, Zethelius B, Vessby B, Lind L. Novel metabolic risk factors for heart failure. J Am Coll Cardiol. 2005;46:2054-60.

Ingelsson E, Sundstrom J, Ärnlöv J, Zethelius B, Lind L. Insulin resistance and risk of congestive heart failure. Jama. 2005;294:334-41.

Ingelsson E, Ärnlov J, Sundstrom J, Lind L. Inflammation, as measured by the erythrocyte sedimentation rate, is an independent predictor for the development of heart failure. J Am Coll Cardiol. 2005;45:1802-6.

Ingelsson E, Ärnlöv J, Sundstrom J, Lind L. The validity of a diagnosis of heart failure in a hospital discharge register. Eur J Heart Fail. 2005;7:787-91.

Koupil I, Leon DA, Byberg L. Birth weight, hypertension and "white coat" hypertension: size at birth in relation to office and 24-h ambulatory blood pressure. J Hum Hypertens. 2005;19:635-42.

Koupil I, Mann V, Leon DA, Lundberg U, Byberg L, Vagero D. Morning cortisol does not mediate the association of size at birth with blood pressure in children born from full-term pregnancies. Clin Endocrinol (Oxf). 2005;62:661-6.

Larsson A, Helmersson J, Hansson LO, Basu S. Increased serum cystatin C is associated with increased mortality in elderly men. Scand J Clin Lab Invest. 2005;65:301-5.

Lind L, Andren B, Arnlov J. The Doppler-derived myocardial performance index is determined by both left ventricular systolic and diastolic function as well as by afterload and left ventricular mass. Echocardiography. 2005;22:211-6.

Olofsson H, Byberg L, Mohsen R, Melhus H, Lithell H, Michaelsson K. Smoking and the risk of fracture in older men. J Bone Miner Res. 2005;20:1208-15.

Warensjo E, Riserus U, Vessby B. Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia. 2005;48:1999-2005.

Zethelius B, Lithell H, Hales CN, Berne C. Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp. Diabetologia. 2005;48:862-7.

 

2004

Ärnlöv J, Ingelsson E, Risérus U, Andrén B, Lind L. Myocardial Performance Index, a Doppler-derived index of global left ventricular function, predicts congestive heart failure in elderly men. European Heart Journal, 2004;24:2220-25

Bjorklund K, Lind L, Zethelius B, Berglund L, Lithell H. Prognostic significance of 24-h ambulatory blood pressure characteristics for cardiovascular morbidity in a population of elderly men. J Hypertens. 2004;22:1691-7

Lind L, Andren B, Sundstrom J. The stroke volume/pulse pressure ratio predicts coronary heart disease mortality in a population of elderly men. J Hypertens. 2004;22:899-905.

Dunder K, Lind L, Lagerqvist B, Zethelius B, Vessby B, Lithell H. Cardiovascular risk factors for stable angina pectoris versus unheralded myocardial infarction. Am Heart J. 2004;147:502-8.

Arnlov J, Vessby B, Riserus U. Coffee consumption and insulin sensitivity. JAMA. 2004;291:1199-201.

Helmersson J, Vessby B, Larsson A, Basu S. Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population. Circulation. 2004;109:1729-34. Epub 2004 Mar 22.

 

2003

Wohlin M, Sundstrom J, Arnlov J, Andren B, Zethelius B, Lind L. Impaired insulin sensitivity is an independent predictor of common carotid intima-media thickness in a population sample of elderly men. Atherosclerosis. 2003;170:181-5.

Björklund K, Lind L, Zethelius B, Andrén B, Lithell H. Isolated ambulatory hypertension predicts cardiovascular morbidity in elderly men. Circulation 2003;107:1297-1302.

Dunder K, Lind L, Zethelius B, Berglund L, Lithell H. Increase in blood glucose concentration during antihypertensive treatment as a predictor of myocardial infarction: population based cohort study. BMJ 2003;326:681-3.

Michaëlsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.

Zethelius B, Byberg L, Hales CN, Lithell H, Berne C. Proinsulin and acute insulin response independently predict type 2 diabetes mellitus in men - report from 27 years of follow-up. Diabetologia 2003;46:20-6.

 

2002

Björklund K, Lind L, Vessby B, Andrén B, Lithell H. Different metabolic predictors of white-coat and sustained hypertension over a 20-year follow-up period: a population-based study of elderly men. Circulation. 2002;106:63-68.

Björklund K, Lind L, Andrén B, Lithell H. The majority of nondipping men do not have increased cardiovascular risk: a population-based study. Journal of Hypertension 2002;20:1501-1506.

Hedman A, Byberg L, Reneland R, Lithell OH. Muscle morphology, self-reported physical activity and insulin resistance syndrome. Acta Physiol Scand 2002;175:325-32.

Lind L, Andrén B. Heart rate recovery after exercise is related to the insulin resistance syndrome and heart rate variability in elderly men. Am Heart J 2002;144:666-72.

Rasmussen SK, Urhammer SA, Berglund L, Jensen JN, Hansen L, Echwald SM, Borch-Johnsen K, Horikawa Y, Mashima H, Lithell H, Cox NJ, Hansen T, Bell GI, Pedersen O. Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes. 2002;51:3561-7.

Zethelius B, Byberg L, Hales CN, Lithell H, Berne C. Proinsulin is an independent predictor of coronary heart disease: Report from a 27-year follow-up study. Circulation. 2002;105:2153-8.

Zethelius, B, Lithell H, Hales CN, Berne C. Insulin resistance and proinsulin - predictors of coronary heart disease. A population-based follow-up study in elderly men using the euglycemic insulin clamp. (manuscript)

 

2001

Byberg L, Smedman A, Vessby B, Lithell H. Plasminogen activator inhibitor-1 and relations to fatty acid composition in the diet and in serum cholesterol esters. Arterioscler Thromb Vasc Biol. 2001;21:2086-92.

Byberg L, Zethelius B, McKeigue PM, Lithell HO. Changes in physical activity are associated with changes in metabolic cardiovascular risk factors. Diabetologia. 2001;44:2134-9.

The DECODE Study Group. Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. Arch Intern Med 2001; 161: 397-405.

Ek J, Andersen G, Urhammer SA, Hansen L, Carstensen B, Borch-Johnsen K, Drivsholm T, Berglund L, Hansen T, Lithell H, Pedersen O. Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians. Diabetologia 2001; 44: 1170-6.

Hansen L, Zethelius B, Berglund L, Reneland R, Hansen T, Berne C, Lithell H, Hemmings BA, Pedersen O. In vitro and in vivo studies of a naturally occurring variant human p85a regulatory subunit of the phosphoinositide 3-Kinase: inhibition of protein kinase B and relationships with Type 2 Diabetes, insulin secretion, glucose disappearance constant, and insulin sensitivity. Diabetes 2001; 50: 690-3.

Hedman A, Andersson PE, Reneland R, Lithell HO. Insulin-mediated changes in leg blood flow are coupled to capillary density in skeletal muscle in healthy 70-year-old men. Metabolism 2001; 50: 1078-82.

Kilander L, Berglund L, Boberg M, Vessby B, Lithell H. Education, lifestyle factors and mortality from cardiovascular disease and cancer. A 25-year follow-up of Swedish 50-year-old men. Int J Epidemiol 2001; 30: 1119-26.

Qiao Q, Tuomilehto J for The DECODE Study Group. Diagnostic criteria of glucose intolerance and mortality. Minerva Med 2001; 92: 113-9.

Sundstrom J, Lind L, Vessby B, Andrén B, Aro A, Lithell HO. Dyslipidemia and an unfavorable fatty acid profile predict left ventricular hypertrophy 20 years later. Circulation 2001; 103: 836-41.

Sundstrom J, Lind L, Valind S, Holmäng A, Björntorp P, Andr B, Waldenström A, Lithell H. Myocardial insulin-mediated glucose uptake and left ventricular geometry. Blood Press 2001; 10: 27-32.

Sundström J, Lind L, Ärnlöv J, Zethelius B, Andrén B, Lithell H. Echocardiographic and electrocardiographic left ventricular hypertrophy predict mortality independently of each other in a population of elderly men. Circulation 2001; 103: 2346-51.

Ärnlöv J, Lind L, Zethelius B, Andrén B, Vessby B, Lithell H. Several factors associated with the insulin resistance syndrome are predictors of left ventricular systolic dysfunction in a male population after twenty years of follow-up. Am Heart J 2001; 142: 720-4.

 

2000

Björklund K, Lind L, Lithell H. Twenty-four hour ambulatory blood pressure in a population of elderly men. J Internal Med 2000; 248: 501-10.

Byberg L, McKeigue PM, Zethelius B, Lithell HO. Birth weight and the insulin resistance syndrome: association of low birth weight with truncal obesity and raised plasminogen activator inhibitor-1 but not with abdominal obesity or plasma lipid disturbances. Diabetologia 2000; 43: 54-60.

Hansen L, Reneland R, Berglund L, Rasmussen SK, Hansen T, Lithell H, Pedersen O. Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity. Diabetes 2000; 49: 298-301.

Hedman A, Reneland R, Lithell H. Alterations in skeletal muscle morphology in glucose tolerant elderly hypertensive men: relationship to blood pressure and heart rate. J Hypertens 2000, 18; 559-65.

Hedman A, Berglund L, Essen-Gustavsson B, Reneland R, Lithell H. Relationships between muscle morphology and insulin sensitivity are improved after adjustment for intra-individual variability in 70-year-old men. Acta Physiol Scand 2000; 169:125-32.

Kilander L, Nyman H, Boberg M, Lithell H. The association between low diastolic blood pressure in middle age and cognitive function in old age. A population-based study. Age Ageing 2000;29:243-8.

Lithell H, Sundström J, Arnlöv J, Björklund K, Hänni A; Hedman A, Zethelius B, Byberg L, Kilander L, Reneland R. Epidemiological and clinical studies on insulin resistance and diabetes. Ups J Med Sci 2000; 105: 135-50.

Mustafa A, Nityanand S, Berglund L, Lithell H, Lefvert AK. Circulating immune complexes in 50-year-old men as a strong and independent risk factor for myocardial infarction. Circulation 2000; 102:2576-81.

Sundstrom J, Lind L, Nyström N, Zethelius B, Andrén B, Hales CN, Lithell H. Left ventricular concentric remodeling rather than left ventricular hypertrophy is related to the insulin resistance syndrome in elderly men. Circulation 2000; 101: 2595-600.

Ärnlöv J, Lind L, Stridsberg M, Andrén B, Lithell H. N-terminal atrial natriuretic peptide and left ventricular geometry and function in a population sample of elderly males. J Internal Med 2000; 247: 699-708.