Papers 1972-1999


Almind K, Frederiksen SK, Bernal D, Hansen T, Ambye L, Urhammer S, Ekstrøm CT, Berglund L, Reneland R, Lithell H, White MF, Van Obberghen E, Pedersen O. Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity. Diabetologia 1999; 42: 1244-9.

Andersson PE, Lind L, Berne C, Berglund L, Lithell HO. Insulin-mediated vasodilation and glucose uptake are independently related to fasting serum nonesterified fatty acids in elderly men. Journal of Internal Medicine 1999; 246: 529-37.

Andrén B, Lind L, Lithell H. The influence of different antihypertensive drugs on left ventricular hypertrophy in a population sample of elderly men. J Hum Hypertens 1999; 13: 499-504.

Andrén B, Lind L, Hedenstierna G, Lithell H. Impaired systolic and diastolic function and ventricular arrhythmia are common in normotensive healthy elderly men with left ventricular hypertrophy. Coron Artery Dis 1999; 10: 111-7.

Koupilová I, Leon DA, McKeigue PM, Lithell HO. Is the effect of low birth weight on cardiovascular mortality mediated through high blood pressure? J Hypertens 1999; 17: 19-25.

Lind L, Andersson PE, Andrén B, Lithell H. Both leg blood flow and the femoral blood flow pattern are related to left ventricular mass in elderly men. Clin Physiol 1999; 19: 275-6.

Nityanand S, Hamsten A, Lithell H, Holm G, Lefvert AK. C4 null alleles and myocardial infarction. Atherosclerosis 1999; 143: 377-81.

Smedman AEM, Gustafsson I-B, Berglund LGT, Vessby BOH. Pentadecanoic acid in serum as a marker for intake of milk fat: relations between intake and metabolic risk factors. Am J Clin Nutr 1999; 69: 22-9.



Byberg L, Siegbahn A, Berglund L, McKeigue P, Reneland R, Lithell H. Plasminogen activator inhibitor-1 activity is independently related to both insulin sensitivity and serum triglycerides in 70-year-old men. Arterioscler Thromb Vasc Biol 1998; 18: 258-64.

Haenni A, Öhrvall M, Lithell H. Atherogenic lipid fractions are related to ionized magnesium status. Am J Clin Nutr 1998; 67: 202-7.

Kilander L, Andrén B, Nyman H, Lind L, Boberg M, Lithell H. Atrial fibrillation is an independent determinant of low cognitive function: a cross-sectional study in elderly men. Stroke 1998; 29: 1816-20.

Kilander L, Nyman H, Boberg M, Hansson L, Lithell H. Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension 1998; 31: 780-6.

McKeigue PM, Lithell HO, Leon DA. Glucose tolerance and resistance to insulin-stimulated glucose uptake in men aged 70 years in relation to size at birth. Diabetologia 1998; 41: 1133-8.

Nilsson J, Jovinge S, Niemann A, Reneland R, Lithell H. Relation between plasma tumor necrosis factor-alpha and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1998; 18: 1199-202.

Sundstrom J, Lind L, Andrén B, Lithell H. Left ventricular geometry and function are related to electrocardiographic characteristics and diagnoses. Clin Physiol. 1998; 18: 463-70.



Kilander L, Nyman H, Boberg M, Lithell H. Cognitive function, vascular risk factors and education. A cross-sectional study based on a cohort of 70-year-old men. J Intern Med 1997; 242: 313-21.

Koupilová I, Leon DA, Lithell HO, Berglund L. Size at birth and hypertension in longitudinally followed 50-70-year-old men. Blood Press 1997; 6: 223-8.

Lind L, Skarfors E, Berglund L, Lithell H, Ljunghall S. Serum calcium: a new, independent, prospective risk factor for myocardial infarction in middle-aged men followed for 18 years. J Clin Epidemiol 1997; 50: 967-73.

Lind L, Sundstrom J, Lithell H. Cardiovascular risk factors and electrographical characteristics and abnormalities in middle-aged males. J Intern Med 1997; 241: 109-13.

Møller AM, Urhammer SA, Dalgaard LT, Reneland R, Berglund L, Hansen T, Clausen JO, Lithell H, Pedersen O. Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4 alfa in caucasians with maturity onset NIDDM. Diabetologia 1997; 40: 980-3.

Reneland R, Andrén B, Lind L, Andersson PE, Hänni A, Lithell H. Circulating angiotensin converting enzyme levels are increased in concentric, but not eccentric, left ventricular hypertrophy in elderly men. J Hypertens 1997; 15: 885-90.

Wu R, Nityanand S, Berglund L, Lithell H, Holm G, Lefvert AK. Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction. Arterioscler Thromb Vasc Biol 1997; 17: 3159-63.



Andrén B, Lind L, Hedenstierna G, Lithell H. Left ventricular hypertrophy and geometry in a population sample of elderly males. Eur Heart J 1996; 17: 1800-7.

Berglund L, Lithell H. Prediction models for insulin resistance. Blood Pressure 1996; 5: 274-7.

Leon DA, Koupilová I, Lithell HO, Berglund L, Mohsen R, Vågerö D, Lithell UB, McKeigue PM. Failure to realise growth potential in utero and adult obesity in relation to blood pressure in 50 year old Swedish men. BMJ 1996; 312: 401-6.

Lind L, Berne C, Andrén B, Lithell H. Relationship between diastolic hypertension and myocardial morphology and function in elderly males with diabetes mellitus. Diabetologia 1996; 39: 1603-6.

Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell UB, Leon DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996; 312: 406-10.

Öhrvall M, Berglund L, Salminen I, Lithell H, Aro A, Vessby B. The serum cholesterol ester fatty acid composition but not the serum concentration of alpha tocopherol predicts the development of myocardial infarction in 50-year-old men: 19 years follow-up. Atherosclerosis 1996; 127: 65-71.



Andrén B, Lind L, Hedenstierna G, Lithell H. Left ventricular hypertrophy and a decreased E/A ratio are common echocardiographic findings even in apparently healthy males of age seventy. Cardiology in the Elderly 1995; 3: 367-371.

Andrén B, Lind L, Larsson K, Hedenstierna G, Ljunghall S, Lithell H. The influence of body composition on left ventricular mass and other echocardiographic and Doppler measurements in 70-year-old males. Clin Physiol 1995; 15: 425-33.

Nityanand S, Dawkins RL, Lithell H, Holm G, Lefvert AK. C4 null alleles in a Swedish population. Eur J Immunogenet 1995; 22: 435-41.

Lind L, Hänni A, Lithell H, Hvarfner A, Sörensen OH, Ljunghall S. 
Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men. Am J Hypertens. 1995 Sep;8(9):894-901.



Vessby B, Aro A, Skarfors E, Berglund L, Salminen I, Lithell H. The risk to develop NIDDM is related to the fatty acid composition of the serum cholesterol esters. Diabetes 1994; 43: 1353-7.

Vessby B, Tengblad S, Lithell H. Insulin sensitivity is related to the fatty acid composition of serum lipids and skeletal muscle phospholipids in 70-year-old men. Diabetologia 1994; 37: 1044-50.



Pollare T, Vessby B, Lithell H. Lipoprotein lipase activity in skeletal muscle is related to insulin sensitivity. Arterioscler Thromb 1991; 11: 1192-203.

Skarfors ET, Lithell HO, Selinus I. Risk factors for the development of hypertension: a 10-year longitudinal study in middle-aged men. J Hypertens 1991; 9: 217-23.

Skarfors ET, Selinus KI, Lithell HO. Risk factors for developing non-insulin dependent diabetes: a 10 year follow up of men in Uppsala. BMJ 1991; 303: 755-60.



Lind L, Pollare T, Hvarfner A, Lithell H, Sorensen OH, Ljunghall S. Long-term treatment with active vitamin D (alphacalcidol) in middle- aged men with impaired glucose tolerance. Effects on insulin secretion and sensitivity, glucose tolerance and blood pressure. Diabetes Res 1989; 11: 141-7.

Skarfors ET, Lithell HO, Selinus I, Åberg H. Do antihypertensive drugs precipitate diabetes in predisposed men? BMJ 1989; 298: 1147-52.



Lithell H, Åberg H, Selinus I, Hedstrand H. Alcohol intemperance and sudden death. Br Med J (Clin Res Ed) 1987; 294: 1456-8.

Ljunghall S, Lind L, Lithell H, Skarfors E, Selinus I, Sorensen OH, Wide L. Treatment with one-alpha-hydroxycholecalciferol in middle-aged men with impaired glucose tolerance - a prospective randomized double-blind study. Acta Med Scand 1987; 222: 361-7.

Ljunghall S, Lithell H, Skarfors E. Prevalence of renal stones in 60-year-old men. A 10-year follow-up study of a health survey. Br J Urol 1987; 60: 10-3.

Skarfors ET, Wegener TA, Lithell H, Selinus I. Physical training as treatment for type 2 (non-insulin-dependent) diabetes in elderly men. A feasibility study over 2 years. Diabetologia 1987; 30: 930-3.



Åberg H, Lithell H, Selinus I, Hedstrand H. Alcohol intemperance and social disability as risk factors for different causes of death. Acta Med Scand 1986; 220: 351-9.

Bolinder J, Lithell H, Skarfors E, Arner P. Effects of obesity, hyperinsulinemia, and glucose intolerance on insulin action in adipose tissue of sixty-year-old men. Diabetes 1986; 35: 282-90.



Åberg H, Lithell H, Selinus I, Hedstrand H. Serum triglycerides are a risk factor for myocardial infarction but not for angina pectoris. Results from a 10-year follow-up of Uppsala primary preventive study. Atherosclerosis 1985; 54: 89-97.



Lithell H, Åberg H, Selinus I, Hedstrand H. The primary preventive study in Uppsala. Fatal and non-fatal myocardial infarction during a 10-year follow-up of a middle-aged male population with treatment of high-risk individuals. Acta Med Scand 1984; 215: 403-9.



Åberg H, Lithell H, Hedstrand H. On cerebrovascular deaths in middle-aged men during a 7-10-year follow- up. Ups J Med Sci 1983; 88: 61-2.

Åberg H, Lithell H. Uppföljning av patienter som uteblev från hypertonikontroll. Opusc Med 1983; 28: 44-45.



Lithell H, Hedstrand H, Gustafsson IB, Hood B. Significant and persistent reduction of serum lipids in asymptomatic men. Acta Med Scand 1981; 210: 181-6.



Åberg H, Hedstrand H, Lithell H. Blood pressure control in a middle-aged male population. A 6-9 year follow-up with special reference to the problem of non-responders. Acta Med Scand 1980; 208: 467-71.



Waern U, Boberg J. Comparison of glucose tolerance, serum insulin, serum lipids and skinfold thickness between 50- and 60-year-old men. Ups J Med Sci 1979; 84: 203-14.

Waern U, Boberg J, Hellsing K. Evaluation of indices of alcohol intake in a population of 60-year-old men in Uppsala, Sweden. Acta Med Scand 1979; 205: 353-60.



Hedstrand H, Åberg H. Familial history in males at low and high risk for cardiovascular disease. Prev Med 1978; 7: 15-21.

Hedstrand H, Ljunghall S, Sundh AG, Waern U. [Giving up smoking by 50-year-old males]. Läkartidningen 1978; 75: 3676-8. Swedish.

Lithell H, Boberg J, Hellsing K, Waern U. Lipoprotein-lipase activity in subcutaneous, adipose tissue in healthy subjects: variation of activity in a population of 60-year-old men. Ups J Med Sci 1978; 83: 45-52.

Ljunghall S, Hedstrand H. Glucose metabolism in renal stone formers. Urol Int 1978; 33: 417-21.



Hedstrand H, Drettner B, Klockhoff I, Svedberg A. Noise and blood-pressure [letter]. Lancet 1977; 2: 1291.

Hedstrand H, Killander A. Anaemia in middle-aged men. Prevalence and aetiology in a population study. Scand J Haematol 1977; 19: 417-23.

Ljunghall S, Hedstrand H. Serum phosphate inversely related to blood pressure. Br Med J 1977; 1: 553-4.

Ljunghall S, Hedstrand H, Hellsing K, Wibell L. Calcium, phosphate and albumin in serum. A population study with special reference to renal stone formers and the prevalence of hyperparathyroidism in middle-aged men. Acta Med Scand 1977; 201: 23-30.



Åberg H, Hedstrand H. Treatment of hypertension in middle-aged men: a feasibility study in a community. Clin Sci Mol Med Suppl 1976; 3: 597s-9s.

Boberg J, Hedstrand H, Wide L. The early serum insulin response to intravenous glucose in patients with decreased glucose tolerance and in subjects with a familial history of diabetes mellitus. Scand J Clin Lab Invest 1976; 36: 145-53.

Hedstrand H. Dietary and drug treatment of hyperlipidaemia. A feasibility study in asymptomatic middle-aged men. Ups J Med Sci 1976; 81: 85-92.

Hedstrand H, Åberg H. Detection and characterization of middle-aged men with hypertension. Acta Med Scand 1976; 199: 273-80.

Hedstrand H, Åberg H. Three-year follow-up of middle-aged men with low blood pressure. Acta Med Scand 1976; 200: 119-121.

Hedstrand H, Åberg H. Treatment of hypertension in middle-aged men. A feasibility study in a community. Acta Med Scand 1976; 199: 281-8.

Hedstrand H, Vessby B. Detection and characterization of hyperlipoproteinaemia in middle-aged men. Ups J Med Sci 1976; 81: 159-66.

Hedstrand H, Vessby B. Serum lipoprotein concentration and composition in healthy 50-year-old men. Ups J Med Sci 1976; 81: 37-48.

Hedstrand H, Waern U, Åberg H. [The reliability of information obtained from middle-aged men about the causes of their parents' death and their age at death]. Läkartidningen 1976; 73: 503-4. Swedish.

Ljunghall S, Hedstrand H. Renal stones and coronary heart disease. Acta Med Scand 1976; 199: 481-5.

Vessby B, Hedstrand H, Olsson U. Lipoprotein composition and lipoprotein interrelations in 50-year-old men with hyperlipoproteinaemia. Ups J Med Sci 1976; 81: 71-8.

Waern U, Hedstrand H, Åberg H. What middle-aged men know of their parents' cause of death and age at death. A comparison between history and death certificate. Scand J Soc Med 1976; 4: 123-9.



Drettner B, Hedstrand H, Klockhoff I, Svedberg A. Cardiovascular risk factors and hearing loss. A study of 1,000 fifty-year-old men. Acta Otolaryngol (Stockh) 1975; 79: 366-71.

Hedstrand H. A study of middle-aged men with particular reference to risk factors for cardiovascular disease. Ups J Med Sci Suppl 1975; 19: 1-61.

Hedstrand H, Åberg H. A 3-year follow-up of middle-aged men with borderline blood pressure. Acta Med Scand 1975; 198: 389-95.

Hedstrand H, Boberg J. Statistical analysis of the reproducibility of the intravenous glucose tolerance test and the serum insulin response to this test in the middle-aged men. Scand J Clin Lab Invest 1975; 35: 331-7.

Hedstrand H, Ljunghall S. Letter: Glucose tolerance in idiopathic calcium-stone formation. Lancet 1975; 1: 1251.

Lithell H, Hedstrand H, Karlsson R. The smoking habits of men with intermittent claudication. Acta Med Scand 1975; 197: 473-6.

Ljunghall S, Hedstrand H. Epidemiology of renal stones in a middle-aged male population. Acta Med Scand 1975; 197: 439-45.

Ljunghall S, Hedstrand H. Letter: Renal stones and coronary heart disease. BMJ 1975; 4: 580.



Hedstrand H, Waern U. [Changes in smoking habits in men over 50-years-old in Uppsala]. Läkartidningen 1973; 70: 2761-2. Swedish.



Hedstrand H. [Results and observations from the Uppsala project]. Läkartidningen 1972; 69: 4653. Swedish.

Hedstrand H, Hood B, Ylanen L. [Insulin response and weight distribution among middle-aged men]. Läkartidningen 1972; 69: 5228-31. Swedish.