Contact: Clinical Geriatrics research group leader Peter Nordström
Visiting address: Husargatan 3, Uppsala Biomedical Centre, entrance A11
The aim of our research is to understand, prevent, diagnos and cure diseases in the elderly population, like dementia, diabetes and cardiovascular diease.
In clinical trials we develop new drugs against these diseases. We are conducting epidemiological and genetic studies to understand the interplay between genes and environment in complex disorders. In clinical research we aim to develop better diagnostic instruments for Alzheimer’s disease. Our molecular research is aiming at disease mechanisms of Alzheimer’s disease and related disorders. The starting point for these studies is genetic discoveries to understand molecular mechanisms involved in dementias. Model systems have been developed in transgenic animals and in cell cultures to test new treatment principles.
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Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis
Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism
Timed Up-and-Go Dual-Task Tests for Early Detection of Dementia Disorder.
Kristin Franzon (2019)
Independent Ageing in Very Old Swedish Men.
Elisabeth Jobs (2014)
Cathepsin S as a Biomarker of Low-grade Inflammation, Insulin Resistance, and Cardiometabolic Disease Risk.
Ylva Cedervall (2014)
Physical Activity and Alzheimer's Disease: Measurements, Observations and Subjective Experiences.
Elisabet Nerpin (2013)